Two members of the Center TRT team take joint supplements regularly, Mike, who's physically fit, under 40 and has a shoulder injury and David, who is over 65 with arthritis. Both, said that after even a week of Arthrozene they were ready to go back to their regular joint supplement (FlexAgain, which topped our best joint supplement lists). All in all the results were both that it did nothing and in comparison to a supplement that was actually helping the difference is quite pronounced.
AprésFlex Boswellia Serrata Extract - 100 MG
Boswellia serrata extract is a type of gum or resin that is extracted from the frankincense trees in India and the Punjab region of Pakistan. It is rich in boswellic acid and has been widely used for centuries in ayurvedic and other types of traditional medicines.
This is due largely to the belief that it can be used to help reduce pain and inflammation in the joints, treat the symptoms experienced by osteoarthritis patients, and even ease the swelling in other parts of the body, such as the brain (1).
Unfortunately, while boswellia serrata extract is becoming a very popular ingredient in joint supplements, it's one of the less effective, and whilst in another supplement this could be a nice extra, in athrozene it's pretty much the lead ingredient.
For starters, most studies on the effects of boswellia serrata extract are still in the very early stages. This means that there is little to no clinical evidence to prove that it can actually offer the benefits that are being claimed.
This means that the 100 mg of boswellia serrata extract found in each serving of Arthrozene is all but guaranteed to do very little. This is even more worrying when you realise that boswellia serrata extract is also the most abundant ingredient in the joint supplement as well.
Collavant N2 - Native Collagen Type II (Chicken Sternum) - 40 MG
Collagen is a type of protein that is among the most abundant in the human body, where it is produced naturally. Split into twenty eight different types, it is said to account for roughly a third of all proteins found within our system and is found in various parts of the body.
Best known for being the foundation of joint cartilage and similar connective tissues, it is also found in places like the bones, hair, nails, skin, and tendinous muscle. It is essential for cells to be effectively glued together, while it also plays a huge role in human metabolism.
As a result, using collagen supplements is a very effective way to support healthy cartilage.
This is even more true of native collagen type II, which is commonly found in chicken and fish and is the main compound that cartilage is made of. It has also been shown by multiple clinical trials to be very beneficial for relieving the mild knee pain caused by osteoarthritis (2).
The problem, however, lies not in the ingredient itself, but in how much is present. Studies say that, in order for collagen supplements to prevent joint pain, joint deterioration, and joint problems, and improve joint function, the optimal dosage is around 10 to 15 grams per day.
Even the minimum daily dosage of collagen type ii required to improve joint health in any way is said to be 2.5 grams. This means that the roughly 40 grams of type II collagen that you will get from taking Arthrozene is massively too low and unlikely to help with joint problems in any way.
Mobilee Natural Chicken Comb Extract (Standardized To 60% Hyaluronic Acid, 5% Collagen Type II & 10% Glucosaminoglycans) - 80 MG
The last of the Arthrozene ingredients, the Mobilee Natural Chicken Comb Extract, contains an additional source of type ii collagen, although at around 4 grams it will not alter the effects that we discussed above. It is then supported by both hyaluronic acid and glucosaminoglycans.
Hyaluronic Acid
Hyaluronic acid is a type of polysaccharide that is best known for its ability to boost cartilage and joint health, strengthen connective tissues, improve joint mobility, flexibility, and elasticity, and relieve pain and stiffness in the joints.
That said, it can also offer a number of other benefits to the human body. This includes it being able to boost the health and elasticity of the skin and reduce its healing time, wrinkles, or the signs of aging, while also improving the health and function of the eyes (3).
However, in order to produce these effects, clinical trials suggest that at least a 200 mg dose of hyaluronic acid must be consumed each day or it needs to be injected onto the site as the stomach breaks almost all of it down.
While Arthrozene have tried to use a proprietary blend to hide the exact dosage of hyaluronic acid that is present, it is easy to work out that it amounts to around 44 mg in every dose.
This means Arthrozene only contains around 20% of what is required to produce results, so the presence of hyaluronic acid in the formula is of absolutely no use at all.
Glucosaminoglycans
Glucosaminoglycans are negatively charged polysaccharide molecules that are present in every bodily tissue of all mammals. In fact, hyaluronic acid is an example of a glucosaminoglycan and is one of the very best ones.
This means that they will provide virtually the same benefits as hyaluronic acid, only to a lesser degree (4).
As we have already established that there is not enough hyaluronic acid present to be of any use, the even more miniscule content of the less effective glucosaminoglycans will therefore be of absolutely no use at all as well.
There aren't many particularly effective ingredients in Arthrozene, especially when you compare it against the current market leaders. If you're looking for a collagen supplement, there are plenty of options with better dosages that also contain boswellia at a cheaper price point, meaning that there's no reason to take arthrozene over one of those. And there's plenty of type 2 collagen supplements on amazon that fit the bill. However, there are a lot of more effective joint supplement ingredients, omega 3 and glucosamine are both clinically proven to the point they can be perscribed. Then there's ginger and turmeric, which contain the active iingredients curcumin and gingerols, which both have a lot more studies backing them for joint pain and health. At least when the right extracts are used and correctly dosed.
That is why we recommend against taking Arthrozene and suggest that you use FlexAgain instead. Which contains the effective dose of boswellia along with 11 other more effective ingredients. We rated it as the best joint supplement currently on the market by some way. It's very effective at joint relief and joint support, sticking to a formula of proven ingredients in their correct doses. Given that it also has a very reasonable price tag, it beats out Arthrozene hands down. And it's not just FlexAgain, we'd recommend most properly dosed generic glucosamine supplements over Arthrozene.
References
1 -https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309643/
2 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970562/
3 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583886/
4 - https://www.ncbi.nlm.nih.gov/books/NBK544295/