Juvenon NuvoFlex Reviews

Is NuvoFlex Any Good?

Published 2nd July 2023

Juvenon Fast Acting NuvoFlex Is Not A Good Supplement.

NuvoFlex, a supplement claiming to provide an all-encompassing solution to joint discomfort, has caught the attention of many. Its promise to rejuvenate joint health and restore youthful mobility is enticing, especially for those struggling with joint pain and stiffness.

The key ingredients in NuvoFlex include FruiteX-B calcium fructoborate, Amla fruit extract, Icariside II, and Vitamin C. And ultimately the lack of transparency in the exact amounts of each ingredient is always a red flag. 

It doesn't take long before everything starts to fall apart and see what we actually have here is a low dosed boron supplement with vitamin C thrown in. The type of calcium used in Nuvoflex is actually only about 5% calcium, [1] the boron is under dosed [2] and most of the other ingredients have only been tested on animals, which 9 times out of 10 doesn't translate to actually working in humans. That's not to say Nuvoflex will do nothing at all, after all vitamin c supplementation has been shown to have some benefits for joint pain, [3] although it's not one of the better options, even if we were just looking at vitamins alone. But, a vitamin c pill would be an awful lot cheaper.

And considering the Nuvoflex comes in as a premium price range joint supplement at $45 a month this is very disappointing. The best product on the market today comes in at $60. And that has more than 10 times the active ingredients, ones actually tested on humans, and that are far more expensive ones to manufacturer at that. 

All in all Nuvoflex looks like a bit of a shameless cash grab of a joint pain supplement and we can't recommend it against, especially with the customer complaints that they haven't been honoring their 60 day money back guarantee. [4]

Best Joint Supplements

Nuvoflex Customer Reviews

The user reviews of Nuvoflex are poor to mixed, when we cross reference all third party platforms which isn't surprising, with the most common complaint being that the supplement simply didn't work. There are some positive nuvoflex reviews of course, most notably on Amazon, but considering that doesn't match up with other negative nuvoflex reviews on platforms like TrustPilot and Better Business Bureau there is always the chance that a few of these have been faked. Although we should say that even accounting for the suspect amazon reviews, it's likely that Juvenon nuvoflex joint support still scores 3*.

Whilst nuvoflex is available on Walmart's website there are no reviews at the time of writing.

There are generally very few reports of Nuvoflex side effects aside from the standard complaints of nausea that isn't uncommon with supplements in general.

There are also complaints of Nuvoflex owners, Juvenon, not honoring their money back guarantee. With customers having to initiate charge backs against Juvenon.

NuvoFlex Ingredients

Vitamin C - At 100% of your RDI this isn't an awful inclusion Vitamin C [5] plays a crucial role in collagen synthesis and has demonstrated some moderate effectiveness in treating certain types of arthritis and musculoskeletal pain relief. {2] Although if you're looking for a simple supplement, omega 3 [6] or vitamin D [7] are both more useful for joint pain and in many cases have been shown to be more effective than over the counter pain options.

Fruite-X (Calcium fructoborate and boron) 220mg - Calcium fructoborate is only about 5% calcium [1], the rest is boron and fructose (aka fruit sugar). So we're not going to be getting nearly calcium enough from this to actually do anything as we're talking 10mg and your RDI is 1200mg. [8] As for the 6mg of boron this could have some potential impact. [9] 10mg of boron has been shown to have some benefit to arthritis symptoms since the 1960's. Again it's not the most effective ingredient, but it's at least got a reasonable amount of backing. [10]

Pro collagen complex 93mg - The Pro collagen complex is made up of alma extract and icariside ii, neither of which are particularly great ingredients for a cartilage or joint pain relief supplement. Mostly because there's no evidence that they're actually going to do anything. Especially when Nuvoflex are suggesting that they'll help stimulate collagen production.

Alma Extract - The claim is that Amla fruit extract helps prevent collagen degradation in the joints, promoting cartilage growth and flexibility. There's no evidence for this at all. There's some evidence that it does function as an anti oxidant, [11] which can have some benefits for joint pain, but there are numerous better options that actually contain compounds which can reduce inflammation markers.

Icariside ii - There are some very lofty claims around Icariside ii and almost no evidence to support it's use as a joint health supplement. There is two studis, yes two, one that suggests that icariside ii can improve bone marrow stem cell quality, in beagles. Yes the dog. [12] And another that shows when mixed with hyaluronic acid and injected into the site it can improve cartilage health in rabbits. [13] Although this was not tested against hyaluronic acid alone which has been shown to have a positive impact by itself when injected into the joints. [14] It's possible that it could have some implications for humans, but the dosage that was given to the 20lb dog is more than would in the Nuvoflex blend. So even if it did manage to transfer to humans, then there isn't really going to be enough.

So as we can see there's almost no backing that the dietary supplement is going to do much to relieve pain or restore youthful cartilage as it claims.

It's not as if there's a shortage of ingredients that can improve joint inflammation, that have dozens of clinical trials that have actually been placebo controlled on humans, so we're really not sure what nuvoflex were thinking with this supplement. Both Alma and Icarside have been studied for other properties, but there isn't really much to suggest that they're going to be effective for joint tissue restoration.

Nuvoflex Review Conclusion

All in all juvenon nuvoflex joint support is just not worth your money. There's 2 ingredients in here that could possibly do something, but nothing you couldn't get from a multivitamin and certainly nothing to justify the price tag of a premium joint supplement.

For $15 a month more you could get something like FlexAgain, that has full doses of 11 clinically proven ingredients, that you'll likely have heard of and can easily find the studies to support. Things like glucosamine, [15] curcumin, [16] methylsulfonylmethane, [17] omega 3 [6] and so on. In short, we'd recommend getting a supplement that's actually been tested on humans with joint pain, not trusting your joint health to a supplement with almost 0 evidence that any of it's ingredients can do anything to relieve joint pain. 

Best Joint Supplements
Criteria Rating
Ingredients 1/10
Pain Relief 2/10
Joint Health 2/10
Swelling 2/10
Value 1/10
Recommended 2/10


1 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256803/
2 - https://pubmed.ncbi.nlm.nih.gov/7889887/
3 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543556/
4 - https://www.bbb.org/us/nv/incline-village/profile/vitamins-and-supplements/juvenon-llc-1166-90021922
5 - https://ods.od.nih.gov/factsheets/VitaminC-HealthProfessional/
6 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362115/
7 - https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/
8 - https://ods.od.nih.gov/factsheets/Calcium-HealthProfessional/
9 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712861/
10 - https://ods.od.nih.gov/factsheets/Boron-HealthProfessional/
11 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878900/
12 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503000/
13 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610878/
14 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469223/
15 - https://www.nccih.nih.gov/health/glucosamine-and-chondroitin-for-osteoarthritis
16 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812094/
17 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372953/